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Explore Our Research / Assessments / Narcolepsy

Narcolepsy

An assessment of oveporexton

Public Meeting
May 2026

Assessment Status

Closed

Public Comments

Closed

  • Overview
  • Full Timeline & Materials
  • Related Assessments & Articles

Interventions of Interest

For questions please contact [email protected].

  • oveporexton (Takeda Pharmaceutical Co., Ltd.)

Final Documents

Final Evidence Report and Meeting SummaryDownload
Final Policy RecommendationsDownload
Report-at-a-GlanceDownload
The ICER Snapshot: for PatientsDownload
Draft Evidence ReportDownload
Response to Public CommentsDownload

Main Review
May 14, 2026

Midwest CEPAC

The Midwest CEPAC’s 2026 public meeting on treatment for narcolepsy

  • Evidence Presentation
  • Public Comments
  • Voting Session
  • Policy Roundtable

ICER STAKEHOLDER OUTREACH AND PUBLIC COMMENTERS LIST

ICER receives input on its reviews from multiple stakeholders, including patients and their families, patient advocacy organizations, clinicians, clinical societies, insurers, and drugmakers. We invite the public to submit recommendations for stakeholders in any of these categories.

The following is a list of organizations from which ICER has requested input, as well as those that have provided unsolicited public comments during the review. Some organizations on the list may appear only because they were invited to provide input, and it should not be assumed that they have responded to ICER’s outreach or agreed to participate in this review.

  • Avadel Pharmaceuticals PLC
  • Day4NAPS
  • Harmony Biosciences
  • Jazz Pharmaceuticals
  • Narcolepsy Network
  • NORD
  • Project Sleep
  • Takeda Pharmaceutical Co. Ltd
  • Wake Up Narcolepsy

To protect patient confidentiality, ICER does not routinely name individual patients or care partners who provided us with input and feedback.

None of these stakeholders are responsible for the final content of ICER’s report, and it should not be assumed that they support any part of the report, which is solely the work of the ICER team and its affiliated researchers.

Narcolepsy Meeting Agenda

Related Assessments & Policy Papers.

Woman_in_passing
10/17/2025

Draft Scoping Document

Download PDF

10/17/2025 - 11/05/2025

Public Comments on Draft Scoping Document

Download PDF

11/18/2025

Revised Scoping Document

Download PDF

11/25/2025

Research Protocol

Please find the research protocol here: https://osf.io/awxuv

01/23/2026

Model Analysis Plan

Please find the model analysis plan here: https://osf.io/knqrg/files/4cmbj

03/12/2026

Draft Evidence Report

Having trouble viewing the report? Click here. 

 

Download PDF

Draft Voting Questions

03/11/2026 - 04/07/2026

Public Comments on Draft Evidence Report

Download PDF

Submit a Public Comment

04/29/2026

Evidence Report

Download PDF

Revised Voting Questions

Response to Public Comments

05/14/2026

Evidence Presentation

Download PDF

06/08/2026

Final Evidence Report and Meeting Summary

Download PDF

Final Policy Recommendations

Report-at-a-Glance

The ICER Snapshot: for Patients

Related Assessments & Policy Papers

Related Press Releases

Institute for Clinical and Economic Review Publishes Final Evidence Report on Treatment for Narcolepsy

Manufacturer setting a price for oveporexton to align with value would help promote broad patient access.

Read More 06/08/2026

Institute for Clinical and Economic Review Releases Evidence Report on Treatment for Narcolepsy

Oveporexton provides a net health benefit compared to currently available treatments; therapy would be cost effective if priced between $50,400 and $59,400 per year.

Read More 04/29/2026

Institute for Clinical and Economic Review Releases Draft Evidence Report on Treatment for Narcolepsy

Public comment period now open until April 7, 2026; Requests to make oral comment during public meeting also being accepted.

Read More 03/12/2026

Institute for Clinical and Economic Review to Assess Treatment for Narcolepsy

Report will be subject of Midwest CEPAC meeting in May 2026; Draft Scoping Document open to public comment until November 5, 2025.

Read More 10/17/2025
Go to Press Releases

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