The effectiveness and value of lecanemab for early Alzheimer’s disease: A summary from the Institute for Clinical and Economic Review’s California Technology Assessment Forum

Journal Article

The Institute for Clinical and Economic Review (ICER) conducted a systematic literature review and cost-effectiveness analysis to evaluatethe health and economic outcomes of lecanemab for early AD. We present the summary of our findings and highlights of the policy discussion with key stakeholders held at a public meeting of the California Technology Assessment Forum (CTAF) […]

ICER Publishes Evidence Report on Lecanemab for Alzheimer’s Disease

Press Release

Currently available evidence is rated as promising but inconclusive to determine whether lecanemab provides a net health benefit over supportive care; the evidence suggests drug would achieve common thresholds for cost-effectiveness if priced between $8,900 - $21,500 per year.

Alzheimer’s Disease

Mar 2023 | Assessment

Interventions of Interest: The independent appraisal committee voted that currently available evidence is not adequate to demonstrate a net health benefit for lecanemab when compared to supportive care. Using best estimates from current data, ICER analyses suggest lecanemab would achieve common thresholds for cost-effectiveness if priced between $8,900 – $21,500 per year. Final Documents ICER’s […]

Empower Your Community With Evidence

What Is In The Final Evidence Report? The full report includes a summary of the public meeting discussion, and any necessary updates to ICER’s conclusions following those discussions. When Is The Final Evidence Report Released? Around three weeks after the public meeting. What is the ICER Snapshot? The Snapshot is a patient-friendly summary of ICER’s […]

ICER’s Collaboration with the Department of Veterans Affairs

ICER’s Collaboration with the Department of Veterans Affairs In 2017, the Department of Veterans Affairs began integrating ICER’s research into its pricing negotiations to provide greater value to Veterans and taxpayers. At the time, there was some consternation from industry, with the National Pharmaceutical Council asking whether the partnership could simply be “…a means to […]