Major depressive disorder (MDD) is a common and debilitating condition; on an annual basis, it is estimated that nearly 14 million Americans will have at least one episode of MDD. While definitions of so-called “treatment-resistant” depression vary, this generally refers to patients with persistent depression after attempted management with two or more medications.

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Interventions of interest, 2019 review: Esketamine (Janssen)

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Final Documents

Below you will find the final documents from the assessment review process:

Public Comments on Draft Evidence ReportDownload
Response to Public CommentsDownload
Report-at-a-GlanceDownload
Final Evidence Report and Meeting SummaryDownload