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Explore Our Research / Assessments / Obesity Management

Obesity Management

An assessment of semaglutide and tirzepatide

Public Meeting
November 2025

Assessment Status

Closed

Public Comments

Closed

  • Overview
  • Full Timeline & Materials
  • Related Assessments & Articles

Intervention of Interest

  • semaglutide (Wegovy®, Novo Nordisk)

For questions please contact [email protected].

View the Key Stakeholder List.

  • tirzepatide (Zepbound®, Eli Lilly and Company)

Final Documents

Final Evidence Report & Meeting SummaryDownload
Report-at-a-GlanceDownload
Final Policy RecommendationsDownload
The ICER Snapshot: for PatientsDownload
Draft Evidence ReportDownload
Response to Public CommentsDownload

Main Review
November 13, 2025

New England CEPAC

The New England CEPAC’s 2025 public meeting on semaglutide and tirzepatide

  • Evidence Presentation
  • Public Comments
  • Voting Questions
  • Policy Roundtable

 

Obesity Management Meeting Agenda

Related Assessments & Policy Papers.

Woman_in_passing

Examining Strategies to Ensure Affordable Access for Obesity Medications

 Apr 2025

Obesity Management

 Sep 2022

Obesity Management

 Jul 2015
04/29/2025

Draft Scoping Document

Download PDF

04/29/2025 - 05/19/2025

Public Comments on Draft Scoping Document

Download PDF

05/29/2025

Revised Scoping Document

Download PDF

06/05/2025

Research Protocol

Please find the research protocol here: https://osf.io/jx2zd

07/24/2025

Model Analysis Plan

Please find the model analysis plan here: https://osf.io/ag5mn

09/09/2025

Draft Evidence Report

Having trouble viewing the report? Click here. 

 

Download PDF

Draft Voting Questions

09/09/2025 - 10/06/2025

Public Comments on Draft Evidence Report

Download PDF

10/29/2025

Evidence Report

Download PDF

Revised Voting Questions

Response to Public Comments

11/13/2025

Evidence Presentation

Download PDF

12/16/2025

Final Evidence Report and Meeting Summary

Download PDF

Report-at-a-Glance

Final Policy Recommendations

The ICER Snapshot: for Patients

Related Assessments & Policy Papers

Examining Strategies to Ensure Affordable Access for Obesity Medications

 Apr 2025

Obesity Management

 Sep 2022 New England CEPAC

Obesity Management

 Jul 2015

Related Press Releases

Institute for Clinical and Economic Review Publishes Final Evidence Report on Treatments for Obesity

Independent committee voted unanimously on the positive net health benefit of all three treatments; final report includes key policy recommendations.

Read More 12/16/2025

Institute for Clinical and Economic Review Publishes Evidence Report on Treatments for Obesity

All three drugs result in substantial weight loss; the therapies are cost-effective, but the very large population appropriate for treatment creates important budgetary issues.

Read More 10/29/2025

Institute for Clinical and Economic Review Releases Draft Evidence Report on Treatments for Obesity

Public comment period now open until October 6, 2025; Requests to make oral comment during public meeting also being accepted.

Read More 09/09/2025

Institute for Clinical and Economic Review to Assess Treatments for Obesity Management

Report will be subject of New England CEPAC meeting in November 2025; Draft Scoping Document open to public comment until May 19, 2025.

Read More 04/29/2025
Go to Press Releases

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