Interventions of Interest: Rucaparib (Rubraca®, Clovis Oncology) Niraparib (Zejula®, Tesaro, Inc.) Olaparib (Lynparza®, AstraZeneca) ICER’s report reviews evidence on the comparative clinical effectiveness and value of poly (ADP-ribose) polymerase (PARP) inhibitors for treatment of ovarian cancer. During the public meeting the Midwest CEPAC voted on key questions related to the clinical effectiveness and value of the […]
Interventions of Interest: remdesivir (VEKLURY®) ICER released the results of its initial analyses to inform public debate of pricing for remdesivir (Gilead Sciences) and other future treatments of COVID-19. Working with external academic partners, ICER has developed ICER-COVID models comprising two alternative pricing paradigms for COVID-19 treatments: 1) “cost recovery” for the manufacturer, representing an […]
Interventions of Interest: voclosporin (Lupkynis™, Aurinia Pharmaceuticals) belimumab (Benlysta®, GlaxoSmithKline) ICER is assessing the comparative clinical effectiveness and value of voclosporin (Lupkynis™, Aurinia Pharmaceuticals) and belimumab (Benlysta®, GlaxoSmithKline) for the treatment of lupus nephritis. Voclosporin was approved for lupus nephritis in 2021, and belimumab is seeking a label expansion for the treatment of lupus nephritis. […]
Intervention of interest: Community health workers Disparities across racial and socioeconomic lines in the utilization of health care services and in patient outcomes continue to plague healthcare systems in the U.S. Policies to address health care disparities have varied, including steps to increase access to health insurance coverage at both the state and federal levels, […]
Intervention of interest: Cardiac nuclear imaging ICER completed a Technology Assessment of cardiac nuclear imaging for the public meeting of the Washington State Health Technology Assessment Program’s Clinical Committee. Date of review: September 2013 Final Documents Below you will find the final documents from the assessment review process:
Interventions of interest: Automated percutaneous lumbar discectomy Coblation nucleoplasty Epidural steroid injections Intradiscal electrothermal therapy Interdisciplinary rehabilitation programs that combine physical therapy, exercise, workplace interventions, and cognitive retraining Interspinous spacer systems Laminectomy Radiofrequency denervation Spinal fusion Surgical lumbar discectomy Low back pain is an exceedingly common complaint, with a lifetime prevalence rangingfrom 11-84% (Walker, 2000). […]
Interventions of Interest: ubrogepant (Ubrelvy™, Allergan) rimegepant (Nurtec™, Biohaven Pharmaceuticals) lasmiditan (Reyvow™, Lilly) Migraine is a common cause of headache and is characterized by episodic, recurrent attacks that are classically pulsatile or throbbing, frequently involve one side of the head, and are associated with nausea and sensitivity to external stimuli such as light, sound, and smells. […]
Intervention of interest: Computed tomography (CT) colonography Conventional colonoscopy Computed tomography colonography (CT colonography or CTC) is a minimally invasiveradiological technique used to provide images of the colon and rectum. CTC has been suggested as an alternative or as complementary to conventional colonoscopy and other population-based screening methods for colorectal cancer. Given that only 40%-60% […]
Intervention of interest: Extracorporeal membrane oxygenation (ECMO) Extracorporeal membrane oxygenation (ECMO) is a form of life support that provides cardiopulmonary assistance outside the body. ECMO may be used to support lung function for severe respiratory failure or heart function for severe cardiac failure. An ECMO circuit can be set up as veno-venous (VV) or veno-arterial (VA). […]
Interventions of interest: Antiarrhythmic drug therapy to return the heart to sinus rhythm Radiofrequency catheter ablation to terminate AF and prevent further episodes Minimally-invasive surgical techniques to terminate AF and prevent further episodes Aspirin, warfarin, and dabigatran for anticoagulation to prevent strokes The WATCHMAN left atrial appendage occlusive device to prevent strokes Atrial fibrillation (AF) […]