Research Type: Assessment

Atopic Dermatitis

Jul 2021 | Assessment

Interventions of Interest: Atopic dermatitis is a chronic relapsing skin condition associated with dry skin and itching. It is characterized by acute flare-ups of pruritic lesions over dry skin. Atopic dermatitis is a subset of the broad classification of eczema. It is the most common skin disease in children, with 50% of patients experiencing onset […]

Cardiovascular Disease: Atherosclerosis

Oct 2018 | Assessment

In June 2018, ICER announced its intention to assess the comparative clinical effectiveness and value of canakinumab (Novartis) for cardiovascular risk reduction in people with atherosclerosis. However, in October 2018, when the Food and Drug Administration declined to approve canakinumab’s expanded indication for atherosclerotic cardiovascular disease, ICER announced it would no longer proceed with its value assessment. […]

Opioid Epidemic: Abuse Deterrent Opioids

Jul 2017 | Assessment

Interventions of Interest: Hysingla® ER (Hydrocodone, Purdue) Vantrela® (Hydrocodone , Teva) Arymo® ER ( Morphine, Egalet) Embeda® (Morphine + naltrexone, Pfizer) Morphabond® (Morphine extended release, Inspirion Delivery Technologies) OxyContin® TR (Oxycodone, Purdue) Xtampza®ER (Oxycodone, Collegium Pharmaceutical Inc) Targiniq® (Oxycodone + naloxone extended release, Purdue) Troxyca® ER (Oxycodone + naltrexone, Pfizer) RoxyBond® (Oxycodone, Inspirion Delivery Technologies) […]

Ovarian Cancer

Sep 2017 | Assessment

Interventions of Interest: Rucaparib (Rubraca®, Clovis Oncology) Niraparib (Zejula®, Tesaro, Inc.) Olaparib (Lynparza®, AstraZeneca) ICER’s report reviews evidence on the comparative clinical effectiveness and value of poly (ADP-ribose) polymerase (PARP) inhibitors for treatment of ovarian cancer. During the public meeting the Midwest CEPAC voted on key questions related to the clinical effectiveness and value of the […]

COVID-19

Jul 2020 | Assessment

Interventions of Interest: remdesivir (VEKLURY®) ICER released the results of its initial analyses to inform public debate of pricing for remdesivir (Gilead Sciences) and other future treatments of COVID-19. Working with external academic partners, ICER has developed ICER-COVID models comprising two alternative pricing paradigms for COVID-19 treatments: 1) “cost recovery” for the manufacturer, representing an […]

Lupus Nephritis

Mar 2021 | Assessment

Interventions of Interest: voclosporin (Lupkynis™, Aurinia Pharmaceuticals) belimumab (Benlysta®, GlaxoSmithKline) ICER is assessing the comparative clinical effectiveness and value of voclosporin (Lupkynis™, Aurinia Pharmaceuticals) and belimumab (Benlysta®, GlaxoSmithKline) for the treatment of lupus nephritis. Voclosporin was approved for lupus nephritis in 2021, and belimumab is seeking a label expansion for the treatment of lupus nephritis. […]

Community Health Workers

Jun 2013 | Assessment

Intervention of interest: Community health workers Disparities across racial and socioeconomic lines in the utilization of health care services and in patient outcomes continue to plague healthcare systems in the U.S. Policies to address health care disparities have varied, including steps to increase access to health insurance coverage at both the state and federal levels, […]

Cardiovascular Disease: Cardiac Nuclear Imaging

Aug 2013 | Assessment

Intervention of interest: Cardiac nuclear imaging ICER completed a Technology Assessment of cardiac nuclear imaging for the public meeting of the Washington State Health Technology Assessment Program’s Clinical Committee. Date of review: September 2013 Final Documents Below you will find the final documents from the assessment review process:

Chronic Pain: Lower Back

Dec 2010 | Assessment

Interventions of interest: Automated percutaneous lumbar discectomy Coblation nucleoplasty Epidural steroid injections Intradiscal electrothermal therapy Interdisciplinary rehabilitation programs that combine physical therapy, exercise, workplace interventions, and cognitive retraining Interspinous spacer systems Laminectomy Radiofrequency denervation Spinal fusion Surgical lumbar discectomy Low back pain is an exceedingly common complaint, with a lifetime prevalence rangingfrom 11-84% (Walker, 2000). […]

Migraine: Acute Therapies

Jan 2020 | Assessment

Interventions of Interest: ubrogepant (Ubrelvy™, Allergan) rimegepant (Nurtec™, Biohaven Pharmaceuticals)  lasmiditan (Reyvow™, Lilly) Migraine is a common cause of headache and is characterized by episodic, recurrent attacks that are classically pulsatile or throbbing, frequently involve one side of the head, and are associated with nausea and sensitivity to external stimuli such as light, sound, and smells. […]