Research Type: Assessment

Attention Deficit Hyperactivity Disorder

Jun 2012 | Assessment

Interventions of interest: Parent behavior training School-based interventions Stimulants Non-stimulants Diagnoses of Attention Deficit Hyperactivity Disorder (ADHD) have risen in recent years, and ADHD is now regarded to be a common condition among children in the United States. While reported prevalence ranges widely between 6-16% depending on location and measurement technique, it has been estimated […]

Behavioral Health Integration

Apr 2015 | Assessment

Intervention of interest: Programs to integrate behavioral health into the primary care setting Providers in the US health care system often assess and treat patients with physical health conditions and behavioral health conditions (e.g., mental health and substance use disorders) in siloes, yet physical and behavioral health are inextricably linked. Up to 70% of physician […]

Beta Thalassemia

Jul 2020 | Assessment

Intervention of Interest LentiGlobin (Zynteglo®, Bluebird Bio) ICER planned to assess the comparative clinical effectiveness and value of LentiGlobin (Bluebird Bio) for the treatment of beta thalassemia. LentiGlobin is an investigational gene therapy currently marketed in Europe under the brand name Zynteglo®. On December 5, 2019, ICER launched our assessment of LentiGlobin, originally intending to conclude the […]

Breast Cancer Screening

Sep 2013 | Assessment

This report examines the comparative effectiveness and value of screening options for women with dense breast tissue, including hand-held and automated breast ultrasound, digital breast tomosynthesis (DBT), and magnetic resonance imaging (MRI). The CTAF Panel voted that the evidence supports supplemental screening of women at high risk for breast cancer, and that screening with MRI, among commonly used screening […]

Cardiovascular Disease: Additive Therapies

Aug 2019 | Assessment

Treatments of Interest: icosapent ethyl (Vascepa®, Amarin Pharma) rivaroxaban (Xarelto®, Janssen Pharmaceuticals) Cardiovascular disease (CVD) is a set of conditions that result primarily from the build-up of plaque in the blood vessels. Depending on where there is build-up, patients can have chest pain (“angina”), muscle pain with walking (“claudication”) and an increased risk of heart […]

Breast Cancer Screening

Dec 2013 | Assessment

Interventions of interest: Hand-held and automated breast ultrasound Digital breast tomosynthesis (DBT) Magnetic resonance imaging (MRI) Following a negative mammogram, many women with dense breast tissue face a decision: whether to receive additional screening, and if so, what modality to use. Many mammography facilities are now informing women with dense breasts about the potential for […]

Breast Cancer Screening

Dec 2014 | Assessment

Interventions of interest: Hand-held and automated breast ultrasound Digital breast tomosynthesis (DBT) Magnetic resonance imaging (MRI) Following a negative mammogram, many women with dense breast tissue face a decision: whether to receive additional screening, and if so, what modality to use. Many mammography facilities are now informing women with dense breasts about the potential for […]

Behavioral Health Integration

May 2015 | Assessment

Intervention of interest: Programs to integrate behavioral health into the primary care setting Providers in the US health care system often assess and treat patients with physical health conditions and behavioral health conditions (e.g., mental health and substance use disorders) in siloes, yet physical and behavioral health are inextricably linked. Up to 70% of physician […]

Depression: Treatment-Resistant

May 2019 | Assessment

Interventions of interest, 2019 review:  Esketamine (SPRAVATO®, Janssen) Major depressive disorder (MDD) is a common and debilitating condition; on an annual basis, it is estimated that nearly 14 million Americans will have at least one episode of MDD. While definitions of so-called “treatment-resistant” depression vary, this generally refers to patients with persistent depression after attempted […]

Depression: Treatment-Resistant

Dec 2011 | Assessment

Interventions of interest, 2011 review: Repetitive transcranial magnetic stimulation, electroconvulsive therapy, vagus nerve stimulation, and cognitive-behavioral therapy/interpersonal therapy Major depressive disorder (MDD) is a common and debilitating condition; on an annual basis, it is estimated that nearly 14 million Americans will have at least one episode of MDD. While definitions of so-called “treatment-resistant” depression vary, this […]