Research Type: Assessment

Cardiovascular Disease: Cardiac Nuclear Imaging

Aug 2013 | Assessment

Intervention of interest: Cardiac nuclear imaging ICER completed a Technology Assessment of cardiac nuclear imaging for the public meeting of the Washington State Health Technology Assessment Program’s Clinical Committee. Date of review: September 2013 Final Documents Below you will find the final documents from the assessment review process:

Chronic Pain: Lower Back

Dec 2010 | Assessment

Interventions of interest: Automated percutaneous lumbar discectomy Coblation nucleoplasty Epidural steroid injections Intradiscal electrothermal therapy Interdisciplinary rehabilitation programs that combine physical therapy, exercise, workplace interventions, and cognitive retraining Interspinous spacer systems Laminectomy Radiofrequency denervation Spinal fusion Surgical lumbar discectomy Low back pain is an exceedingly common complaint, with a lifetime prevalence rangingfrom 11-84% (Walker, 2000). […]

Migraine: Acute Therapies

Jan 2020 | Assessment

Interventions of Interest: ubrogepant (Ubrelvy™, Allergan) rimegepant (Nurtec™, Biohaven Pharmaceuticals)  lasmiditan (Reyvow™, Lilly) Migraine is a common cause of headache and is characterized by episodic, recurrent attacks that are classically pulsatile or throbbing, frequently involve one side of the head, and are associated with nausea and sensitivity to external stimuli such as light, sound, and smells. […]

Colorectal Cancer: CT Colonography

Jan 2008 | Assessment

Intervention of interest: Computed tomography (CT) colonography Conventional colonoscopy Computed tomography colonography (CT colonography or CTC) is a minimally invasiveradiological technique used to provide images of the colon and rectum. CTC has been suggested as an alternative or as complementary to conventional colonoscopy and other population-based screening methods for colorectal cancer. Given that only 40%-60% […]

ECMO

Feb 2016 | Assessment

Intervention of interest: Extracorporeal membrane oxygenation (ECMO) Extracorporeal membrane oxygenation (ECMO) is a form of life support that provides cardiopulmonary assistance outside the body. ECMO may be used to support lung function for severe respiratory failure or heart function for severe cardiac failure. An ECMO circuit can be set up as veno-venous (VV) or veno-arterial (VA). […]

Atrial Fibrillation

Sep 2010 | Assessment

Interventions of interest: Antiarrhythmic drug therapy to return the heart to sinus rhythm Radiofrequency catheter ablation to terminate AF and prevent further episodes Minimally-invasive surgical techniques to terminate AF and prevent further episodes Aspirin, warfarin, and dabigatran for anticoagulation to prevent strokes The WATCHMAN left atrial appendage occlusive device to prevent strokes Atrial fibrillation (AF) […]

Cardiovascular Disease: Coronary Computed Tomographic Angiography

Jul 2012 | Assessment

Interventions of interest: Coronary computed tomographic angiography Coronary computed tomographic angiography (CCTA) is a minimally invasive radiological technique used to provide images of the heart and surrounding vessels. CCTA has been suggested as an alternative or useful complementary approach to other non-invasive methods of diagnosing coronary artery disease (CAD). Date of review: January 2009 For […]

PTSD: Service Dogs

Jan 1970 | Assessment

ICER has been commissioned to conduct an assessment of the cost-effectiveness of service dogs trained in tasks related to post-traumatic stress disorder (PTSD) based on findings from the largest examination to date on the impact of service dogs on PTSD conducted by the U.S. Department of Veterans Affairs (VA). For questions, please contact Meaghan Cummings, […]

High Cholesterol

Feb 2021 | Assessment

Interventions of interest: inclisiran (Leqvio®, Novartis) bempedoic acid (Nexletol®, Esperion Therapeutics) bempedoic acid/ezetimibe (Nexlizet™, Esperion Therapeutics) An independent appraisal committee voted that the evidence is not adequate to demonstrate a net health benefit of bempedoic acid over usual care for the entire population of eligible patients, but is adequate when focused on patients unable to […]

High Cholesterol: PCSK9s

Feb 2019 | Assessment

Interventions of Interest: alirocumab (Praluent®, Regeneron/Sanofi) evolocumab (Repatha®, Amgen) Cardiovascular disease (CVD) is the most common cause of death in the United States and approximately one third of American adults have CVD. Low density lipoprotein cholesterol (LDL) is a major modifiable risk factor for myocardial infarction, stroke, and death from cardiovascular disease. The use of […]